Fig. 1: Manhattan plots of the forward conditional association of the variants in HLA region for NPC risk. | Communications Biology

Fig. 1: Manhattan plots of the forward conditional association of the variants in HLA region for NPC risk.

From: Nasopharyngeal carcinoma MHC region deep sequencing identifies HLA and novel non-HLA TRIM31 and TRIM39 loci

Fig. 1

a This panel shows the original association. Other panels show the association while controlling the locus b rs9391681, c HLA-Aaa-Q62, d rs2523589, e HLA-B*55:02, f rs2517664, g rs9461780, h rs117495548. The horizontal axis shows the genomic position and the vertical axis shows negative log10-transformed P for the association. The red horizontal line corresponds to the significance threshold of P = 5 × 10−8. SNPs (dots), HLA alleles (stars), and amino acid polymorphisms (+) are marked in the plots. The color of the variant represents the r2 between this variant and the controlled variant.

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