Table 1 Sequences and MIC (µM) of the different peptides and antimicrobials used in this work. D amino acids are indicated in lowercase.
Name | Sequence | Source | Strains | ||||
|---|---|---|---|---|---|---|---|
E. coli LMG 15862 | K. pneumoniae LMG 20218 | P. aeruginosa LMG 6395 | A. baumannii LMG 01041 | E. aerogenes LMG 02094 | |||
L-1 | GNNRPVYIPQPRPPHPRL | 0.5 | 5 | >64 | >64 | 8 | |
L-2 | VDKPPYLPRPRPPRRIYNR | 4 | 8 | >64 | 16 | >64 | |
L-3 | VDKGSYLPRPTPPRPIYNRN-NH2 | 3 | 16 | 32 | 8 | >32 | |
L-4 | RLLFRKIRRLKR | 64 | >256 | >128 | >128 | >256 | |
L-5 | RIWVIWRR-NH2 | 3 | 6 | 3 | 2 | 5 | |
L-6 | RRLFRRILRWL-NH2 | 2 | 4 | 3 | 2 | 8 | |
L-7 | GIGKHVGKALKGLKGLLKGLGEC | 6 | 12 | 13 | 2 | 8 | |
L-8 | KRIVQRIKKWLR-NH2 | 4 | 64 | 16 | 16 | 32 | |
L-9 | -RIVQRIKKW-R-NH2 | This work | 256 | >256 | >256 | >256 | >256 |
L-10 | -RIVQRIKKWL--NH2 | This work | 32 | 64 | 16 | 128 | >256 |
L-11 | -RIVQRIKKWLR-NH2 | This work | 12 | 32 | 16 | >64 | 128 |
L-12 | -KIVQRIKKWLR-NH2 | This work | 16 | 32 | 16 | 128 | 256 |
L-13 | -AIVQRIKKWLR-NH2 | This work | 12 | 24 | 16 | 128 | 128 |
L-14 | -RIRKRIKKWLR-NH2 | This work | 16 | >256 | 16 | >256 | >256 |
L-15 | -RIKRRIKKWLR-NH2 | This work | 24 | >256 | 32 | >256 | >256 |
D-11 | rivqrikkwlr-NH2 | This work | 4 | 32 | 16 | 8 | 32 |
D-11R | rlwkkirqvir-NH2 | This work | 8 | 32 | 16 | 64 | 32 |
Vancomycin | 64 | 128 | 128 | 32 | 192 | ||
Nisin | 12 | 48 | 36 | 6 | 32 | ||
