Fig. 5: Hyperthermia decreases β-catenin expression through STAT3 signaling. | Communications Biology

Fig. 5: Hyperthermia decreases β-catenin expression through STAT3 signaling.

From: Molecularly targeted photothermal ablation improves tumor specificity and immune modulation in a rat model of hepatocellular carcinoma

Fig. 5

In both mouse (HCA-1) and rat (McA-RH7777) HCC cell lines, hyperthermia to 43 C decreased β-catenin expression relative to control. This effect was abrogated by the use of the STAT3 inhibitor Stattic. Each bar represents a single biological sample, and the error bars reflect variation among technical replicates.

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