Fig. 6: Analysis of T-cell responses in PBMC after LASV challenge. | Communications Biology

Fig. 6: Analysis of T-cell responses in PBMC after LASV challenge.

From: Systemic viral spreading and defective host responses are associated with fatal Lassa fever in macaques

Fig. 6

a The number of CD8+ and CD4+ T cells in the blood is presented according to the time after LASV infection. b The percentage of circulating CD8+ (left) and CD4+ (right) T cells expressing CD69, KI67, Annexin V and 7AAD (Ann/7AAD), perforin (Perfo), GrzB, CD95, or CD279 is shown according to the time after LASV infection. Results show the mean ± SEM of control (n = 3), AV (n = 4), and Josiah (n = 6) animals. Statistical analyses were performed and are presented as in Fig. 1. Individual values can be found in Supplementary data 1.

Back to article page