Table 1 Gene transcripts that acquire high levels of non-synonymous C>U RNA editing in M1 macrophages.
From: RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization
Gene | Genomic coordinate of RNA editing (GRCh38/hg38) | RNA editing event | SC average editing level | A3A KD average editing level | SC/KD ratio |
|---|---|---|---|---|---|
SDHB | chr1:17044825 | NM_003000:exon2:c.C136T:p.R46X | 0.227 | 0.040 | 5.70 |
THOC5 | chr22:29508462 | NM_001002879:exon20:c.C2047T:p.R683C | 0.750 | 0.316 | 2.38 |
ZNF124 | chr1:247157042 | NM_001297568:exon4:c.C580T:p.R194C | 0.589 | 0.117 | 5.04 |
ARSB | chr5:78984968 | NM_198709:exon2:c.C281T:p.S94L | 0.434 | 0.074 | 5.86 |
ATXN2 | chr12:111516348 | NM_001310121:exon10:c.C866T:p.S289L | 0.396 | 0.049 | 8.04 |
SLC37A2 | chr11:125080652 | NM_198277:exon7:c.C566T:p.S189F | 0.342 | 0.049 | 7.00 |
GAA | chr17:80107625 | NM_001079804:exon4:c.C761T:p.S254L | 0.341 | 0.021 | 16.39 |
PCGF3 | chr4:743578 | NM_006315:exon7:c.C367T:p.R123W | 0.300 | 0.066 | 4.55 |
CDYL2 | chr16:80684900 | NM_152342:exon2:c.C254T:p.S85L | 0.248 | 0.018 | 13.77 |
S1PR2 | chr19:10224709 | NM_004230:exon2:c.C197T:p.S66L | 0.220 | 0 | N/A |
