Fig. 5: Correlation between regional cortical expression of neurotransmitter receptor genes and structural–functional connectivity decoupling in PD. | Communications Biology

Fig. 5: Correlation between regional cortical expression of neurotransmitter receptor genes and structural–functional connectivity decoupling in PD.

From: Organisational and neuromodulatory underpinnings of structural-functional connectivity decoupling in patients with Parkinson’s disease

Fig. 5: Correlation between regional cortical expression of neurotransmitter receptor genes and structural–functional connectivity decoupling in PD.

Spearman correlations between regional cortical expression of adrenergic, cholinergic (muscarinic and nicotinic), and dopaminergic receptors and difference in structural–functional connectivity coupling seen between PD and controls (left) and PD low visual performers vs PD high visual performers (right). Full gene names in Supplementary Table 2. Results colour coded according to receptors: red: adrenergic, green: cholinergic, purple: dopaminergic, blue: serotoninergic receptors. Bars with stronger (rather than fainter) colours indicate statistically significant relationships (FDR-corrected p > 0.05).

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