Table 1 Demographics and clinical assessments.
Characteristic | Controls n = 30 | PD high visual performers n = 58 | PD low visual performers n = 30 | Statistic |
|---|---|---|---|---|
Age (years) | 66.8 (9.3) | 66.8 (9.3) | 64.4 (8.0) | 0.001b |
Male (%) | 13 (43.3) | 13 (43.3) | 48 (54.5) | 0.334 |
Years of education | 17.7 (2.5) | 17.7 (2.5) | 17.1 (2.9) | 0.098 |
Vision | ||||
Contrast sensitivity (Pelli–Robson)a | 1.8 (0.2) | 1.8 (0.2) | 1.7 (0.1) | <0.001b |
Acuity (LogMar)a | −0.08 (0.2) | −0.08 (0.2) | −0.08 (0.1) | 0.441 |
Colour vision (D15) | 1.3 (1.3) | 1.1 (0.8) | 1.6 (1.8) | 0.334 |
General cognition | ||||
MOCA | 28.8 (1.3) | 28.8 (1.3) | 27.9 (2.4) | 0.003b |
MMSE | 29 (1.1) | 29 (1.1) | 28.9 (1.3) | 0.573 |
Mood | ||||
HADS anxiety | 3.7 (3.4) | 3.7 (3.4) | 5.9 (3.1) | 0.023b,c |
HADS depression | 1.9 (1.4) | 1.9 (1.4) | 4.1 (3.1) | <0.001b,c |
Disease-specific measures | ||||
Years from diagnosis | – | 3.7 (2.6) | 4.5 (2.6) | 0.061 |
UPDRS total score | – | 44.2 (25.5) | 49.9 (26.8) | 0.315 |
UPDRS motor score | – | 23. 2 (14.1) | 24.3 (14.8) | 0.785 |
LEDD | – | 411.1 (273.5) | 479.4 (201.2) | 0.099 |
RBDSQ | – | 4.4 (2.7) | 4.0 (2.1) | 0.832 |
Image quality metrics | ||||
Coefficient of joint variationd | 0.69 (0.3) | 0.69 (0.3) | 0.67 (0.2) | 0.925 |
Entropy focus criteriond | 0.59 (0.1) | 0.59 (0.1) | 0.59 (0.1) | 0.167 |
Total Signal to noise ratioe | 1.89 (0.2) | 1.89 (0.2) | 1.85 (0.2) | 0.314 |
Mean framewise displacemente | 0.17 (0.1) | 0.17 (0.1) | 0.19 (0.1) | 0.056 |