Fig. 5: Chemical shift perturbations of residues in three regions of ligand binding site at 308 K. | Communications Biology

Fig. 5: Chemical shift perturbations of residues in three regions of ligand binding site at 308 K.

From: Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites

Fig. 5: Chemical shift perturbations of residues in three regions of ligand binding site at 308 K.

A Overlays of the 1H-15N HSQC spectra of residues in three regions of the ligand-binding site of the MERS-CoV macro domain alone and a series of NAD metabolites titrations. B The decrease in intensity of cross-peaks and the chemical shift difference of residues selected are plotted against the concentration of titrated NAD metabolites.

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