Fig. 3: Effects of SCPs-A6 and G6 on the cell morphologies and ultrastructures of MDR E. coli CVCC195.

Bacteria in mid-logarithmic growth were treated with peptides or antibiotic at 4 × MIC for 2 h (n = 3 independent experiments). a SEM images. The scalebar represents 2 and 1 μm. b TEM images. Both N6 and PMB were used as controls. Red arrows indicated typical disruptions, which was caused by peptides (filamentous substances, disappearance of membranes, leakage of contents and ghosts) or PMB (protrusions). The scalebar represents 5, 1, and 0.2 μm.