Fig. 2: The performance of the NDR metric in various drug-treated and control conditions, assuming that the negative control has no effect and the positive control is 100% lethal. | Communications Biology

Fig. 2: The performance of the NDR metric in various drug-treated and control conditions, assuming that the negative control has no effect and the positive control is 100% lethal.

From: A normalized drug response metric improves accuracy and consistency of anticancer drug sensitivity quantification in cell-based screening

Fig. 2

a Dynamic change in readout for different growth rates in positive control (shades of red) and constant growth in negative control (green). b Percent inhibition (PI) values computed for the conditions shown in Figs. 1b and 2a. c Growth rate (GR) values computed for the conditions shown in Figs. 1b and 2a. d NDR metric computed for the conditions shown in Figs. 1b and 2a. e Dynamic change in readout for different growth rates in negative control (shades of green) and constant growth rate in positive control (red). f PI metric computed for the condition shown in Figs. 1b and 2e. g GR metric computed for the condition shown in Figs. 1b and  2e. h NDR metric computed for the condition shown in Figs. 1b and 2e.

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