Table 1 Model summaries of sample metadata and association with the gut microbiome.

From: The gut microbiome but not the resistome is associated with urogenital schistosomiasis in preschool-aged children

Variable

n

Bacteria

Fungi

p value

SSExplain

SSTotal

FDR

p value

SSExplain

SSTotal

FDR

Age (years)

113

0.004

1344.6

82733.4

0.024

0.082

128.6

9489.2

0.197

Sex

113

0.172

878.1

83200.0

0.258

0.439

82.8

9534.9

0.671

Village

113

0.012

1254.0

82824.0

0.039

0.060

140.4

9477.4

0.180

S.h. infection status (pos/neg)

113

0.013

1185.1

82892.9

0.039

0.001

339.0

9278.7

0.006

S.h. infection intensity

113

0.001

1514.5

82563.6

0.012

0.001

670.1

8947.7

0.006

Malnourished, yes/no (WHZ)

107

0.866

589.1

78498.2

0.913

0.830

59.5

9145.6

0.830

Stunted, yes/no (HAZ)

109

0.407

754.6

79751.0

0.542

0.611

71.5

9227.2

0.671

Months breastfed

90

0.082

954.9

64235.8

0.140

0.470

75.2

6985.0

0.671

Months solid food introduced

102

0.913

573.1

75583.0

0.913

0.615

73.5

8792.0

0.671

Previous praziquantel treatment

105

0.071

991.9

77387.4

0.140

0.233

101.6

8934.5

0.466

Amoxicillin (yes/no)

76

0.771

646.6

55603.4

0.913

0.531

78.4

6567.3

0.671

Co-trimoxazole (yes/no)

76

0.030

1083.6

55166.4

0.072

0.048

158.3

6487.4

0.180

  1. The table represents PERMANOVA output for bacteria and fungi genera. Classification of nutritional status was based on a cut off <−2 Z scores52. Schistosome infection intensity was log transformed (log10 [egg count + 1]). S.h. S. haematobium, WHA weight-for height Z scores, HAZ height-for-age Z scores, pos/neg positive/negative, p value unadjusted p value, FDR adjusted p value (FDR-corrected), SSExplain explained sum of squares, SSTotal total sum of squares.
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