Fig. 3: Cross-frequency coupling between hippocampus and neocortex. | Communications Biology

Fig. 3: Cross-frequency coupling between hippocampus and neocortex.

From: Phase-based coordination of hippocampal and neocortical oscillations during human sleep

Fig. 3

Coupling strengths (dPACZ) for HPC-NC (a) and NC-HPC PAC (b). White outlines indicate clusters of significantly greater than zero coupling across patients (cluster-based permutation test). c Comparisons of HPC-NC and NC-HPC PAC for each SO-based N3 cluster (indicated in panels (a) and (b) with arrows). *P < 0.05, **P < 0.01, ***P < 0.001 (Wilcoxon signed rank test, uncorrected). d, e SO phase (with respect to sine wave) at which faster activity is maximally expressed across patients for HPC-NC (d) and NC-HPC (e) PAC. Colored lines indicate group averages, with green indicating significant (P < 0.05) deviations from uniformity, and red nonsignificance. N = 10.

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