Fig. 7: Hydroxy-octadecenoic acids (HOEAs) promote mast cell degranulation and MCF-7 breast adenocarcinoma cell growth. | Communications Biology

Fig. 7: Hydroxy-octadecenoic acids (HOEAs) promote mast cell degranulation and MCF-7 breast adenocarcinoma cell growth.

From: Hydroxy-octadecenoic acids instead of phorbol esters are responsible for the Jatropha curcas kernel cake’s toxicity

Fig. 7

Effects of hydroxy-octadecenoic acids (HOEAs) on the expression of extracellular tryptase of human LAD2 mast cells (a) and on the proliferation of human MCF-7 breast adenocarcinoma cells (b). The box-and-whisker statistics plots were produced by Excel 2016 (n = 3 biologically independent samples for a, n = 4 biologically independent samples for b); differences were identified using two-tailed T-Test, DMSO vs. HOEAs, p = 0.013 (a), DMSO vs. Oleic acid, p = 0.01 (a), HOEAs vs. Oleic acid, p = 0.005 (a). The DMSO group received the same amount of DMSO as the treated groups alone; Control was blank without any treatment. Hydroxy-octadecenoic acids is an isomeric mixture of 11-hydroxy-9E-octadecenoic acid, 12-hydroxy-10E-octadecenoic acid and 12-hydroxy-10Z-octadecenoic acid obtained from the kernel cake of Jatropha.

Back to article page