Fig. 8: Hydroxy-octadecenoic acids disable mouse intestinal and uterine tissues. | Communications Biology

Fig. 8: Hydroxy-octadecenoic acids disable mouse intestinal and uterine tissues.

From: Hydroxy-octadecenoic acids instead of phorbol esters are responsible for the Jatropha curcas kernel cake’s toxicity

Fig. 8

Effects of hydroxy-octadecenoic acids on the dysfunction of mouse intestinal (a) and uterine (b) tissues. The intestinal tissue (a) and uterine tissue (b) were consecutively treated with hydroxy-octadecenoic acids at increasing concentrations indicated, and finally treated by acetylcholine (Ach) or oxytocin, respectively. Tmax, maximal tension; Tmin, minimal tension; Tavg, average tension. Hydroxy-octadecenoic acids is an isomeric mixture of 11-hydroxy-9E-octadecenoic acid, 12-hydroxy-10E-octadecenoic acid and 12-hydroxy-10Z-octadecenoic acid obtained from the kernel cake of Jatropha.

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