Fig. 6: Regional linkage disequilibrium plot for rs76647377. | Communications Biology

Fig. 6: Regional linkage disequilibrium plot for rs76647377.

From: Genome-wide association study of Buruli ulcer in rural Benin highlights role of two LncRNAs and the autophagy pathway

Fig. 6

Evidence of association with Buruli ulcer (−log10(P); left y-axis) for the variants located in the vicinity of rs76647377 (kb; x-axis). The distribution of recombination rates in this region is also given (cM/Mb; Right y-axis; light blue line). For the replicated SNP (i.e. rs76647377), the blue diamond corresponds to the result observed in the combined analysis, whereas the blue circle corresponds to the result observed in the GWAS only. A color-coded scheme is used to display the degree of LD of the proximal variants with the replicated SNP (red: r² ≥ 0.8, orange: 0.5 ≤ r² < 0.8, and yellow: 0.2 ≤ r² < 0.5). Only variants with an r² > 0.5 are labeled. Known genes in the chromosomal region are plotted, with arrows indicating their orientation.

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