Fig. 5: Comparison of genomic and epigenomic features between TAD and inter-TAD regions.
From: Rice 3D chromatin structure correlates with sequence variation and meiotic recombination rate
a Histone and DNA modifications. TADs are higher in repressive and lower in active chromatin marks compared to inter-TAD regions. b Transposable element (TE) permutation analysis. Most TE classes are overrepresented in TADs. Green line—observed number of overlaps, grey line—mean of simulated overlaps, red line—significance threshold. Thousand permutations were performed. c Recombination rate. Recombination rate is significantly higher in TADs compared to inter-TAD regions. d Number of meiotic crossovers. Meiotic crossovers are significantly overrepresented in TADs. Green line—observed number of overlaps, grey line—mean of simulated overlaps, red line—significance threshold. *p < 0.01, two-tailed Wilcoxon rank sum test, statistical tests were performed on non-log-transformed values. Center line, median; box limits, upper and lower quartiles; whiskers, 1.5× interquartile range; points, outliers.
