Fig. 2: Blood eGenes network and cell enrichment. | Communications Biology

Fig. 2: Blood eGenes network and cell enrichment.

From: Single-cell expression and Mendelian randomization analyses identify blood genes associated with lifespan and chronic diseases

Fig. 2

a Reduced network topology of key central nodes and interactions. b–d Analysis of single-cell RNA-sequencing data of monocytes and dendritic cells (GEO accession number GSE94820). b t-SNE graphs showing a cell cluster expressing CLEC9A. c Heatmap of gene enrichment in CLEC9A− and CLEC9A+ cell clusters. d Violin plots showing data distribution (vertical bars illustrate median and 95% CI) and comparing expression in CLEC9A− and CLEC9A+ cell clusters.

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