Fig. 5: Virophage replication is associated with a progressive degradation of Tupanvirus viral factories. | Communications Biology

Fig. 5: Virophage replication is associated with a progressive degradation of Tupanvirus viral factories.

From: A virophage cross-species infection through mutant selection represses giant virus propagation, promoting host cell survival

Fig. 5

Transmission electron microscopy images of Tupanvirus viral factories infected with mixture containing mutant Guarani at different stages of infection. a The first virophage progeny could be observed at 16 h p.i. (arrow), at this stage, the virus factories seem to be still intact. b–e Later in the cycle, at 20 h, 24 h, 30 h and 36 h p.i., respectively, the replication of the virophage (arrows) causes a remarkable fragmentation of the virus factories and seems to be correlated with their progressive degradation, affecting Tupanvirus particle morphogenesis.

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