Fig. 5: Multimodal characteristics of liposomal nanotheranostics. | Communications Biology

Fig. 5: Multimodal characteristics of liposomal nanotheranostics.

From: Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

Fig. 5

a Contrast measurements (also known as radiodensity) of designed gold nanoparticles (AuNPs) and graphene quantum dots (GQDs)-loaded liposomal nanohybrids named as NFGL at various concentrations (5–100 µg/mL) using a clinical TOSHIBA 64 CT clinical scanner with 5 mm slice thickness and 1 s rotation time compared with parent liposome (loaded with AuNPs and GQDs), revealing the presence of AuNPs (high electron coefficient and density) within the liposomal framework. b Emission performance of NFGL and compared with parent liposomes and PBS using the in vivo imaging system (IVIS) showing the better contrast ability for deep tissue penetration, and indicating the presence of GQDs within liposomal assembly. c Time-dependent photothermal transduction performance of NFGL nanohybrids at 0.5 mg/mL concentration using 750 nm of NIR light irradiation (1 W/cm2) compared with parent liposome (n = 3), ensuring the potential impact of phototriggered therapy. d Digital photographs showing dispersion of NFGL at ambient conditions, and during laser exposure after 1 h and 24 h of time periods.

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