Fig. 3: Serial block-face scanning electron microscopy images of mitochondrial ultrastructure in the experimental groups. | Communications Biology

Fig. 3: Serial block-face scanning electron microscopy images of mitochondrial ultrastructure in the experimental groups.

From: The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats

Fig. 3

Original SBF–SEM serial images were acquired and processed into 3D reconstructions using ImageJ (a). Mitochondria were then analyzed for contract site analysis (b) and intermitochondrial network connectivity (d), with quantified data in panels c and e, respectively. N = 6–8 for normoxic, N = 8 for IR + Saline/Elamipretide groups *P < 0.05 versus normoxic, #P < 0.05 versus I/R saline. Three-dimensional reconstructions of these images are presented in the Supplemental Figures, Fig. S5. Scale bar represents 500 nm.

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