Fig. 2: Time-of-addition analysis of antiviral activities of ouabain and digoxin.
From: Inhibition of Na+/K+ ATPase blocks Zika virus infection in mice

a Antiviral effects of digoxin and ouabain in each group, determined by the plaque assay. b Huh-7 cells were electroporated with the ZIKV replicon were treated with digoxin and ouabain at the indicated concentration, respectively, and luciferase activities were determined as indicated. Data are represented as the means ± SDs from at least three independent experiments. ****P < 0.0001, ***P < 0.001, *P < 0.05.