Fig. 6: Glycine and l-serine but not glycolate can ameliorate the antioxidant capacity of C. elegans mutants unable to metabolize glycolate to glyoxylate.
From: Glycolate combats massive oxidative stress by restoring redox potential in Caenorhabditis elegans
a Total glutathione (GSH + GSSG) levels, b GSSG levels, and c ratio of GSH to GSSG in wild type (N2), single (ghpr-1), and triple (ghpr-1, ldh-1, gox-1) mutant animals exposed to 100 mM H2O2 and supplemented or not with 10 mM glycolate (GA), 100 μM glycine or 500 μM l-serine. Values were determined after 3 days of treatment and normalized to number of worms. Error bars represent standard error of the mean (n = 3).
