Table 2 Comparison of the metabolic profiles of NHPs.

From: Amylin deposition activates HIF1α and 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 (PFKFB3) signaling in failing hearts of non-human primates

Groups

CTL

HF

Age (years)

12 ± 2

18 ± 1*

Body weight (kg)

4.7 ± 0.51

8.3 ± 1.02**

BMI (kg/m2)

23 ± 2

47 ± 6**

Fasting blood glucose (mg/dL)

67 ± 6.7

93 ± 23

Fasting insulin (μIU/mL)

21.7 ± 4

58.9 ± 27.12

Glycated hemoglobin (HbA1C) (%)

4 ± 0.09

4.35 ± 0.37

Serum albumin(g/L)

36.38 ± 2.1

38.35 ± 1.67

Serum cholesterol (mmol/L)

2.11 ± 0.09

3.80 ± 0.56*

Serum triglyceride (mmol/L)

0.37 ± 0.03

0.82 ± 0.14**

Serum HDL (mmol/L)

1.07 ± 0.10

1.58 ± 0.33

Serum LDL (mmol/L)

0.92 ± 0.15

2.10 ± 0.89

  1. Data represent mean ± SEM. *P < 0.05, **P < 0.01 by Student’s t test. Control (CTL) group, n = 7; heart failure (HF) group, n = 6. BMI body mass index, HbA1C hemoglobin A1C, HDL high-density lipoprotein, LDL low-density lipoprotein.
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