Fig. 5: Phylogenetic tree of LNSs and linalool synthases in plants, fungi, and bacteria.

Two major clades, plant and microbial, are clearly segmented. (R)-linalool synthases are marked with black triangles (▲), (S)-linalool synthases with white triangles (△), LNSs with black circles (●), and nerolidol synthases with black rectangles (■). PpSTS25 is a myrcene/linalool synthase from Postia placenta20. For plant and bacterial enzymes, UniProt accession number are used. D8RNZ9, more similar to the bacterial LNS than plant ones, was a LNS isolated from the nonseed plant Selaginella moellendorffii (Spikemoss). Details of all the enzymes are in Supplementary Table S3.