Fig. 4: Interaction effects on rCBF between task and lesion.

Interaction effects of task and lesion showing the change in task relation between pre- and post-lesion period. a, b Brain areas with a significant interaction effect between task condition and lesion. Red-yellow and blue-light blue show a significant increase and decrease of task relationship in the post-lesion period compared to the pre-lesion period, respectively. c, d The relationship between rCBF (corrected for global signal) and task condition in the contra- and ipsilesional IPS, respectively (regions of Interests were 5 × 5 × 5 voxels around local maxima of post > pre contrast; ipsilesional IPS: x = −7.5, y = −3.0, z = 31.0 mm; contralesional IPS: x = 9.5, y = −3.5, z = 28.5 mm; red squares in each inset). Box plots and regression lines are shown. Blue open boxes with a dotted line indicate monkey C, pre-lesion data. Red open boxes with a dotted line indicate monkey T, pre-lesion data. Blue filled boxes with a continuous blue line indicate monkey C, post-lesion data. Red filled boxes with a continuous line indicate monkey T, post-lesion data. Regression coefficients: ipsilesional IPS in pre-lesion period, monkey C = 0.04, monkey T = −0.12; ipsilesional IPS in post-lesion period, monkey C = 0.26, monkey T = 0.29; contralesional IPS in pre-lesion period, monkey C = −0.12, monkey T = −0.04; contralesional IPS in post-lesion period, monkey C = 0.29, monkey T = 0.14.