Table 1 Data sets used for analyses.

Source	Name	Tissue source	Sample type	n	References
Human	SCLC cell lines/ NCI/Hamon Center	SCLC	Cell line	69	This study
Human	Horie_2016	SCLC	Cell line	4	²⁸
Human	Pozo_2020	SCLC	Cell line	4	²⁹
Human	Cañadas_2014	SCLC	Cell line	6	⁵⁶
Human	Drapkin_2018	SCLC	PDX	19	⁵⁷
Human	Rudin_2012	SCLC	Tumor	29	⁹
Human	George_2015	SCLC	Tumor	81	¹⁰
Human	Jiang_2016	SCLC	Tumor	79	⁸⁰
Human	SCLC tumors (this study)	SCLC	Tumor	18	This study
Human	expO	Lung cancer	Tumor	109	⁸²
Human	Rousseaux_2013	Lung cancer	Tumor	286	^81,82
Human	CCLE	Pan-cancer	Cell line	–^b	²⁵
Human	TCGA	Pan-cancer	Tumor	10535	⁵³
Human	TARGET	Pan-cancer	Tumor	734	⁵³
Mouse	Lim_2017	SCLC	Pooled FACS-sorted tumor cells^a	6	¹⁸
Human	Travaglini_2020	Healthy lung	Single cell	9384^c	⁴²
Mouse	Ouadah_2019	Healthy lung	Single cell	46^c	⁷

PDX patient-derived xenografts, FACS fluorescence-activated cell sorting, scRNA-seq single-cell RNA sequencing.
^aIn Lim_2017, Rb1^flox/flox;p53^flox/flox;p130^flox/flox;Rosa26^mTmG; Hes1^GFP/+ GEMM SCLC tumors were initiated by Ad-CMV-Cre, sorted by Tomato and GFP to obtain relatively pure tumor cells.
^bCCLE data sets were used in multiple analyses with different numbers of cell lines; ^cCells.

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