Fig. 1: Biophysical characterization of CEACAM1 IgV mutants.
From: Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium
Thermal stability and molecular size analysis of hCEACAM1 WT and GFCC′ face mutants. a Variations in melting point temperature (TM) determined by differential scanning fluorimetry (DSF) are shown for WT and mutant hCEACAM IgV. b Size exclusion chromatography and multi-angle light scattering (SEC-MALS) differential refractive index (dRI) chromatograms and calculated molecular weights are displayed for WT (black), V39A (red), I91A (green), N97A (blue), and E99A (orange).
