Fig. 7: A proposed model to explain how MLT delays ovarian aging.
From: Melatonin delays ovarian aging in mice by slowing down the exhaustion of ovarian reserve

The depletion of ovarian follicle reserve is the direct cause of ovarian aging. MLT slows down the exhaustion of follicle reserve by inhibiting the activation, growth, and atresia of follicles in PreOR and DOR, thus delaying ovarian aging.