Fig. 7: Graphic summary of OB pathways involved in social discrimination. | Communications Biology

Fig. 7: Graphic summary of OB pathways involved in social discrimination.

From: Top-down acetylcholine signaling via olfactory bulb vasopressin cells contributes to social discrimination in rats

Fig. 7: Graphic summary of OB pathways involved in social discrimination.

Blue, green, and gray arrows represent excitatory and red lines inhibitory pathways indicated by this study and our previous publication8. The cells within the dashed circle indicate the excitatory network within the same home glomerulus. Dashed pathways were confirmed but not fully dissected on the synaptic level. Green pathways are related to vasopressin signaling, gray pathways to sensory input or behavioral output and black pathways are based on findings from literature. Question marks indicate potential dendritic and axonal release of VP in the OB. Axonal projections innervate GL, EPL, MCL, and sGCL. EPL external plexiform layer, eTC external tufted cell, GL glomerular layer, HDB horizontal limb of the diagonal band of broca, MC mitral cell, MCL mitral cell layer, mTC middle tufted cell, ON olfactory nerve, sGCL superficial granule cell layer, VPC vasopressin cell.

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