Table 1 Clinical and laboratory features of patients with HFRS stratified by five stages or two disease phases (acute and convalescent).
From: HTNV infection of CD8+ T cells is associated with disease progression in HFRS patients
Acute phase | Convalescent phase | ||||
|---|---|---|---|---|---|
Febrile | Hypotensive | Oliguric | Diuretic | Convalescent | |
(n = 45) | (n = 24) | (n = 75) | (n = 108) | (n = 28) | |
Age (years) | 48.0 [27.8, 55.0] | 41.0 [34.5, 55.0] | 45.0 [29.0, 54.5] | 46.0 [29.0, 54.5] | 49.0 [29.8, 56.0] |
Sex | |||||
Male | 28 (62.2%) | 17 (70.8%) | 56 (74.7%) | 80 (74.1%) | 18 (64.3%) |
Female | 17 (37.8%) | 7 (29.2%) | 19 (25.3%) | 28 (25.9%) | 10 (35.7%) |
White blood cell count, ×109/L | 12.6 [8.1, 16.3] | 14.1 [8.9, 33.0] | 10.9 [7.9, 16.0] | 8.1 [6.4, 10.1] | 7.1 [6.2, 9.0] |
Platelet count, ×109/L | 65.0 [40.8, 87.5] | 43.0 [25.0, 85.2] | 84.0 [53.0, 137.0] | 196.5 [107.5, 254.8] | 205.0 [144.5, 282.0] |
Hemoglobin, g/L | 122.0 [111.8, 133.5] | 123.0 [93.5, 134.2] | 114.0 [98.0, 125.0] | 111.5 [100.0, 129.0] | 122.0 [103.5, 134.0] |
Lymphocyte count, ×109/L | 3.6 [2.4, 5.1] | 2.5 [1.8, 9.1] | 2.7 [1.5, 4.4] | 1.8 [1.3, 2.3] | 1.7 [1.4, 2.4] |
Neutrophil count, ×109/L | 6.7 [4.4, 8.8] | 5.5 [4.2, 12.8] | 7.3 [4.4, 9.4] | 4.8 [3.7, 6.1] | 4.1 [3.4, 5.2] |
Alanine transaminase (ALT), U/L | 53.0 [37.5, 75.0] | 68.5 [46.8, 105.8] | 61.0 [44.0, 92.0] | 55.5 [34.0, 81.5] | 48.0 [36.5, 73.2] |
Aspartate transaminase (AST), U/L | 55.0 [46.0, 76.0] | 90.5 [48.2, 164.8] | 57.0 [42.0, 120.0] | 43.0 [31.0, 61.0] | 33.5 [27.2, 49.5] |
AST/ALT | 1.1 [0.9, 1.5] | 1.5 [1.0, 1.9] | 1.0 [0.8, 1.4] | 0.8 [0.6, 1.0] | 0.7 [0.6, 1.0] |
Creatinine, μmol/L | 96.0 [72.1, 196.2] | 146.9 [105.2, 254.8] | 260.2 [167.1, 356.5] | 186.3 [104.2, 301.9] | 98.4 [66.2, 202.6] |
Albumin, g/L | 28.4 [27.1, 31.2] | 31.6 [27.2, 33.7] | 31.1 [29.5, 34.4] | 36.0 [33.2, 40.7] | 36.2 [33.4, 38.7] |
Uric acid, μmol/L | 302.8 [216.6, 446.0] | 251.6 [141.9, 350.9] | 217.9 [121.9, 415.6] | 431.9 [296.0, 533.8] | 390.0 [274.4, 454.4] |
Blood urea nitrogen, mmol/L | 9.0 [5.2, 13.4] | 9.5 [7.1, 15.6] | 12.1 [8.6, 16.3] | 13.0 [7.7, 17.9] | 6.2 [5.1, 14.6] |
Glomerular filtration rate, mL/min | 66.7 [35.2, 109.9] | 38.4 [20.8, 67.0] | 25.6 [15.8, 35.4] | 36.3 [19.2, 68.4] | 73.6 [22.8, 97.5] |
Prothrombin time, s | 10.2 [9.9, 10.7] | 11.1 [10.6, 12.2] | 10.6 [10.1, 11.8] | 11.4 [10.7, 12.1] | 10.6 [10.5, 12.1] |
Potassium, mmol/L | 3.4 [3.2, 3.8] | 3.7 [3.4, 3.9] | 3.6 [3.3, 4.0] | 3.6 [3.1, 3.9] | 3.8 [3.2, 4.1] |
Sodium, mmol/L | 137.6 [133.1, 141.8] | 135.1 [132.3, 138.2] | 135.5 [133.6, 139.3] | 139.6 [136.6, 143.4] | 141.0 [138.7, 142.9] |
