Fig. 4: Cell-type-specific high-frequency bursting.

a Spiking activity of an example L5tt recording during quiescent episodes with single spikes indicated by black ticks and spikes at supracritical frequency (≥100 Hz) by red ticks, respectively. b Example traces of a single spike (upper trace) and burst events of 2–4 consecutive spikes at supracritical frequency (≥100 Hz). c The median fraction of high-frequency bursts detected during spontaneous spiking activity (quiescent episodes) depends on the cutoff criteria (1st–3rd quartile range omitted for clarity). Arrow indicates the cutoff criterion used in subsequent analyses. d Scatterplot illustrating spike rate (APs/s) of individual recordings during quiescent episodes and burst rate (events/s) (Pearson correlation, Rho 0.66, p < 0.0001). e Burst rate (events/s) during quiescent (Q) and touch (T) windows, respectively for different excitatory cell types. Boxplots show median as central mark, the edges of the box the 25th and 75th percentiles, the whiskers extend to the most extreme data points, and the outliers are plotted individually. f Burst length as the number of action potentials (APs), relative to the total number of events observed during quiescent windows. g Analogous to (f) , but for Touch windows.