Fig. 4: PTPRZ1, PDGFa, ANXA2, and COL8A1 expression are modulated by Gal-3. | Communications Biology

Fig. 4: PTPRZ1, PDGFa, ANXA2, and COL8A1 expression are modulated by Gal-3.

From: Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells

Fig. 4: PTPRZ1, PDGFa, ANXA2, and COL8A1 expression are modulated by Gal-3.The alt text for this image may have been generated using AI.

a Functional annotation clustering of gene set enrichment analysis comparing Ge518 shCtrl vs. shGal-3. Histograms show the enrichment score of each family of genes. b Hierarchical clustering of Ge518 shCtrl vs. shGal-3 based on the differential expressed genes. c mRNA expression was determined by qPCR in Ge518 infected by shRNA Control (shCtrl) vs. shGal-3 (n = 2–3). d mRNA expression was determined by qPCR in Ge269 infected by shCtrl vs. shGal-3 (n = 2–3). Data are represented as mean ± SEM (*p < 0.05, **p < 0.01, and ***p < 0.001), Student t test. ns nonsignificant.

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