Fig. 8: Association of FUT6 null alleles to allergy-related parameters. | Communications Biology

Fig. 8: Association of FUT6 null alleles to allergy-related parameters.

From: FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression

Fig. 8: Association of FUT6 null alleles to allergy-related parameters.

Plots were generated with data from individuals of the SSIC cohort21,22. a IgE. The box and whisker plots, box representing the upper and lower quartile, central line representing the median, and the minimum and maximum values indicate the distribution of the plasma amounts of allergen-specific IgE reactive to house dust mite (HDM) (left panel) and total IgE (right panel) in reference to the imputed FUT6 status (+/+ (n = 124), +/− (n = 84), −/− (n = 14)). b Eosinophil frequency. The y-axis displays the frequency of eosinophils of the total leukocyte count. c Skin prick Test (SPT). The box and whisker plots, box representing the upper and lower quartile, central line representing the median, and the minimum and maximum values indicate the response of allergen-specific skin prick tests. The parameters displayed are the diameter of the erythema (left panel) and the wheal (right panel) induced by HDM. In all experiments, the significance was determined by Kruskal–Wallis test. The nominal p values are indicated in the figure.

Back to article page