Fig. 1: Intergenerational and transgenerational inheritance. | Communications Biology

Fig. 1: Intergenerational and transgenerational inheritance.

From: Exploring the evidence for epigenetic regulation of environmental influences on child health across generations

Fig. 1: Intergenerational and transgenerational inheritance.

Depiction of inheritance patterns from the parent (F0) generation to the child (F1), grandchild (F2), and great-grandchild (F3) in humans and animals. An exposure in F0 can directly affect the developing fetus (F1) and the germ cells in F2; therefore, both routes of transmission are considered intergenerational. Transgenerational effects may be observed beginning with the F3 generation.

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