Fig. 3: Non-neuronal and immature olfactory cell localization of ACE2 in MOED.
Cellular profile of ACE2 expression in the MOED by immunohistochemistry. a Co-expression of ACE2 (in pink) with apical CK18+ sustentacular cells (CK18, in red). b, c Basal co-expression of ACE2 with CK5 + HBCs (CK5, in red; (b)) and SOX2 + GBCs (SOX2, in red; (c)). Nuclei of sustentacular cells (c) also expressed SOX2. Colocalization between red and pink signals is highlighted in light gray (a–c). Nuclei are counterstained with Dapi (DAPI, in blue). Horizontal basal cells (HBCs, (b)), globose basal cells (GBCs, (c)). Representative protein expression profile obtained from heterozygous OMP-GFP mice of 9 (a, b) and 7 months old (c). Scale bars are 5 μm (a, b) and 10 μm (c).
