Fig. 1: Experimental system. | Communications Biology

Fig. 1: Experimental system.

From: Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates

Fig. 1

a Schematic of flow and tissue factor exposure in a jugular vein puncture wound. Tissue factor exposure leads to coagulation factor activation, e.g., thrombin generation. b, c Bleeding time cessation times at the two different locations where punctures were performed and the effect of mouse sex on bleeding times, mean plus and minus standard deviation. Comparative positioning of the thrombus (red fluorescence in (d)). Upon opening the jugular vein (d) and embedding in plastic (e, f). Schematic of repeated, SBF-SEM imaging across the puncture wound hole. The resulting image slices are positioned so that flow is from left to right and the direction of progressive block face exposure into the plane of the page.

Back to article page