Fig. 1: Primary sensory cortices are not fully developed at birth but show extensive microstructural tissue growth during the first 6 months of life.
From: Infants’ cortex undergoes microstructural growth coupled with myelination during development
a Right hemisphere sagittal (top) and ventral-temporal (bottom) T1 maps in units of seconds [s] displayed on an inflated cortical surface of an example infant across time. Left to right: cortical T1 at 8 days (newborn), 104 days (~3 months), and 181 days (~6 months) of age (red/yellow: higher T1; purple: lower T1). b Primary sensory-motor areas35: V1, A1, M1, and S1 shown on the cortical surface of this infant. c T1 distributions across voxels of each area show a leftward shift from newborns (darker colors) to 6-month-olds (lighter colors). Solid lines: mean distribution; Shaded region: standard error of the mean across 10 infants at each timepoint. NB: newborn; 3 mos: 3-month-old; 6 mos: 6-month-old. Darker colors indicate younger infants. d T1 linearly decreases with age in primary sensory-motor areas. Each dot: mean T1 per area per infant. Line: Linear mixed model line fit. e–f Same as in c,d for mean diffusivity (MD). Shaded portions represent 95% confidence intervals. For panels c–f, Ntotal = 30, 10 infants at each time point (newborn, ~3-month-old, ~6-month-old).
