Fig. 1: Human B cells and monoclonal antibodies (mAbs) bind with ranging affinities to arabinomannan (AM). | Communications Biology

Fig. 1: Human B cells and monoclonal antibodies (mAbs) bind with ranging affinities to arabinomannan (AM).

From: Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes

Fig. 1

Binding of human B cells to AM by flow cytometry for a subject T1 (CD20+, CD27+, IgG+), b subject L1 (CD19+, IgG+). Binding of mAbs to H37Rv AM by ELISA at varying concentrations from c subject T1, and d subject L1. Florescence-minus-one (FMO) controls were used to set conservative AM+ gates and IgG+ gates for sorting. Each bar represents the mean and standard deviation from three experiments.

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