Fig. 5: Combination of high-affinity human mAbs to distinct AM epitopes can detect low levels of LAM and AM in urine by sandwich ELISA. | Communications Biology

Fig. 5: Combination of high-affinity human mAbs to distinct AM epitopes can detect low levels of LAM and AM in urine by sandwich ELISA.

From: Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes

Fig. 5

Detection of serial dilutions of LAM and AM generated from the clinical Mtb strain CDC1551 and spiked into urine of a healthy volunteer by a L1AM04 (10 µg/mL) as a capture and T1AM09 (250 ng/mL) as a detection mAb, and b murine mAb CS-35 (10 µg/mL) as a capture and human mAb A194 (250 ng/mL) as a reference. The data shown are representative from two separate experiments.

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