Fig. 6: T1AM09 and L1AM04 show distinct binding to mycobacterial strains by immunofluorescence (mycobacteria were grown without detergent to preserve the capsule). | Communications Biology

Fig. 6: T1AM09 and L1AM04 show distinct binding to mycobacterial strains by immunofluorescence (mycobacteria were grown without detergent to preserve the capsule).

From: Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes

Fig. 6

Binding of human IgG1 mAbs (10 µg/mL) and polyclonal serum IgG (1:100 dilution) to virulent laboratory (H37Rv and Erdman) and clinical strains (CDC1551 and Beijing) of Mtb, avirulent strains of the Mtb complex group (H37Ra and BCG Pasteur) and nontuberculous mycobacteria (M. avium and M. abscessus) for a T1AM09; b L1AM04; and c Binding of positive (sera from T1 and L1) and negative (isotype-matched mAb to a flavivirus) controls to H37Rv. Scale bar represents 10 µm.

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