Fig. 7: T1AM09 and L1AM04 show distinct binding to mycobacterial strains by whole-cell ELISA (mycobacteria were grown without detergent to preserve the capsule). | Communications Biology

Fig. 7: T1AM09 and L1AM04 show distinct binding to mycobacterial strains by whole-cell ELISA (mycobacteria were grown without detergent to preserve the capsule).

From: Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes

Fig. 7

Binding of human IgG1 mAbs (50 µg/mL) and polyclonal serum IgG (1:20 dilution) to virulent laboratory (H37Rv and Erdman) and clinical strains (CDC1551 and Beijing) of Mtb, avirulent strains of the Mtb complex group (H37Ra and BCG Pasteur) and nontuberculous mycobacteria (M. avium and M. abscessus) assessed at optical density (OD) of 450 nm for a T1AM09; b L1AM04; c Isotype-matched negative control IgG1 mAb to a flavivirus; and positive controls, d Subject T1 serum; and e Subject L1 serum. The data shown are representative from two separate experiments.

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