Fig. 2: Differentially methylated regions from whole genome bisulfite data.
From: Charting differentially methylated regions in cancer with Rocker-meth
a Lollipop plot showing the number of regions with gain (red) and loss (blue) of methylation detected by Rocker-meth across 6 tumor types from TCGA. b Dot plot of the fraction of cancer genome within DMRs (DMR burden) for gain and loss of methylation events across the different tumor types. c Box plot reporting the distribution of DMR lengths (base pairs, bp) for gain and loss of methylation events across tumor types and genic features. d Fraction of the overlap between partially methylated domains (PMD) and highly methylated domains (HMD) segments and the tumor type-specific hypo-blocks identified by Rocker-meth.
