Table 1 Baseline characteristics of participants in the Generation R Study and BMDCS.
From: CYP11B1 variants influence skeletal maturation via alternative splicing
Generation R Study | ||||
|---|---|---|---|---|
N (3510) Mean (SD) | Boys (49%) Mean (SD) | Girls (51%) Mean (SD) | P ΔSex | |
Age (years) | 9.80 (0.33) | 9.80 (0.35) | 9.78 (0.31) | 0.05 |
Height (m) | 1.42 (0.07) | 1.42 (0.06) | 1.41 (0.07) | 0.04 |
Z_Height | −0.07 (1.00) | −0.05 (0.94) | −0.09 (1.05) | 0.25 |
BMI (kg/m²) | 17.54 (2.71) | 17.41 (2.55) | 17.66 (2.85) | 0.01 |
Z_BMI | 0.27 (1.03) | 0.30 (1.03) | 0.24 (1.04) | 0.05 |
Skeletal age (years) | 9.42 (1.29) | 9.27 (1.49) | 9.56 (1.05) | <0.001 |
BMDCS | ||||
|---|---|---|---|---|
N (1047) Mean (SD) | Boys (47%) Mean (SD) | Girls (53%) Mean (SD) | P ΔSex | |
Age (years) | 10.91 (1.39) | 10.83 (1.37) | 10.98 (1.40) | 0.10 |
Height (m) | 1.45 (0.10) | 1.44 (0.10) | 1.46 (0.10) | 0.01 |
Z_Height | 0.21 (0.81) | 0.16 (0.79) | 0.25 (0.83) | 0.07 |
BMI (kg/m2) | 18.47 (2.76) | 18.17 (2.55) | 18.73 (2.91) | <0.001 |
Z_BMI | 0.25 (0.89) | 0.23 (0.90) | 0.27 (0.89) | 0.44 |
Skeletal age (years) | 10.83 (1.94) | 10.48 (1.85) | 11.13 (1.97) | <0.001 |
