Fig. 2: EWCE-derived cell-type enrichments for 12 GTEx CNS regions. | Communications Biology

Fig. 2: EWCE-derived cell-type enrichments for 12 GTEx CNS regions.

From: Mitochondrial-nuclear cross-talk in the human brain is modulated by cell type and perturbed in neurodegenerative disease

Fig. 2

The left-hand y axis refers to the GTEx CNS region, while the right-hand facet labelling refers to the cell-type. For each cell-type in each region, the metric for enrichment is shown as the number of standard deviations from the bootstrapped mean (SD from mean, indicated by the colour bar). A dark green colour indicates a higher number of standard deviations from the mean, while lighter green indicates fewer standard deviations from the mean. The x axis indicates which scRNA-seq dataset the underlying cell-type specificity matrix was derived from. For each association, the following asterisks are overlaid to indicate the multiple test correction threshold passed: *0.05/12 < P < 0.05; **0.05/12*6 < P < 0.05/12; ***P < 0.05/12*6.

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