Fig. 4: Differentially expressed genes, enrichments, and gene regulatory networks for cross-modal cell clusters. | Communications Biology

Fig. 4: Differentially expressed genes, enrichments, and gene regulatory networks for cross-modal cell clusters.

From: Manifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics

Fig. 4: Differentially expressed genes, enrichments, and gene regulatory networks for cross-modal cell clusters.

a The gene expression levels across all 3654 cells for Top 10 differential expressed genes (DEGs) of each cross-modal cell cluster in the mouse visual cortex. The cell clusters were identified by the gaussian mixture model (Methods). The expression levels are normalized (Methods). b The select enriched biological functions and pathways of DEGs (GO and KEGG terms with adjusted p value <0.05) and representative electrophysiological features (adjusted p value <0.05) in Cluster 1 of the mouse visual cortex. c Gene regulatory networks that link transcription factors (TFs, cyan) to target genes (Orange) in Cluster 1 of the mouse visual cortex.

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