Fig. 5: Performance for different methods tested on tyrosine kinase inhibitors. | Communications Biology

Fig. 5: Performance for different methods tested on tyrosine kinase inhibitors.

From: PremPLI: a machine learning model for predicting the effects of missense mutations on protein-ligand interactions

Fig. 5

a Pearson correlation coefficient for each tyrosine kinase inhibitor. * and ** indicate statistically significant difference from zero in terms of PCC with p-value < 0.05 and p-value < 0.01 (t-test), respectively. b Performance of six different methods tested on Abl-axitinib complex. PCC and RMSE in red: all 26 mutations; PCC and RMSE in black: mutations with three red dots removed.

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