Fig. 5: Quantitative mathematical modeling of the repressilator. | Communications Biology

Fig. 5: Quantitative mathematical modeling of the repressilator.

From: Independent control of amplitude and period in a synthetic oscillator circuit with modified repressilator

Fig. 5

a Relation diagram of the quantitative model. The model has three parts, the regulation of period, amplitude, and output. b Simulation of the quantitative model. The x-axis represents the concentration of salicylate (I1), the y-axis represents the concentration of IPTG (I2). Different values of amplitude and period are represented by different colors. The results of experiments are shown in the form of hollow dots with corresponding colors. c MI metrics between the inputs, amplitude, and period. MI (Amp, T), MI (I2, Amp), and MI (I1, T) are close to zero, meaning that the amplitude and period are not coupled and the regulation of the two inputs are independent.

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