Fig. 1: In vitro analog of operant conditioning. | Communications Biology

Fig. 1: In vitro analog of operant conditioning.

From: Neuronal population activity dynamics reveal a low-dimensional signature of operant learning in Aplysia

Fig. 1

a Schematic of isolated ganglia for simultaneous extracellular electrophysiology and VSD imaging. b Example BMP. c Timeline and training paradigm. d, e Examples of nerve activity before and after contingent (d) or yoked training (e). f Contingently trained preparations had a greater increase in the rate of iBMPs compared to yoked preparations (Wilcoxon signed-rank test, P = 0.03, W = −26, N = 7; medians: contingent = 0.27, yoked = 0.10 BMPs/min). g No significant difference was observed for other patterns (P = 0.94, W = −2, N = 7; medians: contingent = 0.10, yoked = 0.07 BMPs/min). BMP rates were pretest-subtracted. Individual datums represent preparations. Box plots show median (line), quartiles (box), and range (whiskers).

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