Fig. 1: Effect of C-terminal truncation on αSN fibrillation.
Log-log plots of fibrillation half-times versus concentrations whose slope provides the scaling exponent γ. The plots reveal a single linear correlation for αSN125 and longer constructs and the growing prominence of a flat region at high protein concentration for shorter constructs. Each point represents the half-time of a ThT curve (i.e., the time to reach half the maximal fluorescence value) from a fibrillation experiment carried out at the indicated αSN concentration.
