Fig. 2: Genomic representation of the hCRISPRs. | Communications Biology

Fig. 2: Genomic representation of the hCRISPRs.

From: CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue

Fig. 2: Genomic representation of the hCRISPRs.

a Genomic location of the hCRISPRs (n = 12,572) visualized as an ideogram, each window represents a human chromosome (chromosome 1:22 and XY). The y-axis of the data-tracks shows the number of hCRISPRs, binned per genomic Mb (in blue; bins with >15 hCRISPR are colored red). b Overlap of the hCRISPRs with known annotations from GENCODE v33 (transcript support level 1 and 2). Overlap was based on a minimum of five base pairs between hCRISPR foci and gene foci; several hCRISPRs overlap with >1 gene. Frequencies (x-axis) are plotted on a log10 scale. c Overlap of the hCRISPRs with known genetic features from GENCODE v33 (transcript support level 1 and 2). Overlap was based on a minimum of five base pairs between hCRISPR foci and gene foci; several hCRISPRs overlap with >1 gene. Frequencies (x-axis) are plotted on a log10 scale. d Overlap of the hCRISPRs with known human repeat families. Overlap was based on a minimum of five base pairs between hCRISPR foci and repeat foci; several hCRISPRs overlap with >1 repeat. e Top 30 (based on frequency) of repeat families overlapping with the hCRISPRs.

Back to article page